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Exploit in vivo imaging technology to study disease pathogenesis and assess drug effectiveness.
31 Oct 2017
Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.
14 Sep 2017
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi
Journal of Medicinal Chemistry
23 Aug 2017
Biological factors that impinge on Chagas disease drug development.
17 Oct 2016
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage
16 Oct 2016
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy
01 Aug 2015
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging
Antimicrob Agents Chemother
16 Sep 2014
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection