Dr Michael Marks

Associate Professor
michael.marks [at] lshtm.ac.uk

Michael is Associate Professor at LSHTM. His PhD, which was funded by the Wellcome Trust, focused on understanding the impact of azithromycin mass administration on treponemal infections as part of a strategy to eliminate yaws in the Solomon Islands including work on disease mapping and the evaluation of diagnostic tests. He was a lead investigator on a WHO sponsored trial of treatment of yaws in Ghana and Papua New Guinea and collaborate with Oriol Mitjà on studies to optimise community treatment strategies for yaws in PNG. He is the principal investigator on a new EDCTP evaluation of a LAMP assay for yaws (2020-2022) in Ghana, Cote d’Ivoire and Cameroon.

His research interests now include all of the human treponematoses including both Treponema pallidum subsp. pallidum (the causative agent of syphilis) and T.pallidum subsp. pertenue (the causative agent of yaws) on which he actively collaborates with Professor Nick Thomson on the application of next-generation sequencing tools to our understanding in these important diseases.

He is also involved in a number of studies on the epidemiology and control of scabies, which is endemic in the Pacific region and has recently been adopted as an NTD by the World Health Organization. He has active collaboration with Andrew Steer, in Melbourne, and John Kaldor, in Sydney, on a number of studies to better understand the use of mass treatment strategies to control scabies in endemic communities.

As well as work on yaws and scabies he is interested in strategies for the integrated control of neglected tropical diseases. He is a lead investigator on several studies exploring the possibility of combining MDA programmes for multiple NTDs into a single intervention in Ethiopia and Papua New Guinea. Along with Rachel Pullan & Steve Walker he is a lead investigator on an NIHR funded project (2019-2023) on integrated control strategies for NTDs of the skin including buruli ulcer, yaws, cutaneous leishmaniasis and leprosy in Ghana and Ethiopia.

Michael is a member of the World Health Organization Department of Control of Neglected Tropical Diseases Diagnostic Technical Advisory Group and is on the executive steering committee for the International Alliance for the Control of Scabies.

Details of grants and work Michael is involved in are also available on ORC-ID